有關腎臟癌的臨床表徵
Clinical Manifestations of Renal Cell Carcinoma
1.常見間歇無痛性血尿,腫瘤生長在腎臟內,容易引起毛細血管破裂出血,導致尿液帶血。
Hematuria: Intermittent, painless hematuria is a common symptom. Tumors growing within the kidney can easily rupture capillaries, leading to blood in the urine.
2.腫瘤增大,會壓迫周圍組織,引起腰痛。如果腫瘤長得很大,甚至可以在腹部摸到腫塊。
Pain and Mass: As the tumor grows, it can press on surrounding tissues, causing flank pain. In cases of large tumors, an abdominal mass may be palpable.
3.腎臟有調節鈣磷代謝的功能。當腎功能受損時,腎臟無法有效地排出磷,為了維持鈣磷平衡,副甲狀腺會分泌更多的副甲狀腺素,導致骨骼中的鈣釋放到血液中,引起高血鈣。
Hypercalcemia: The kidney plays a role in calcium and phosphorus metabolism. When kidney function is impaired, the kidneys cannot effectively excrete phosphorus. To maintain calcium-phosphorus balance, the parathyroid glands secrete more parathyroid hormone, leading to the release of calcium from bones into the bloodstream, resulting in hypercalcemia.
4.紅血球生成素 (EPO):這是一種由腎臟分泌的激素,主要功能是刺激骨髓產生紅血球。
腎功能變差確實會導致紅血球生成素EPO不足,但這並非腎臟癌的典型臨床表徵。腎臟癌造成的貧血,更常見的原因是腫瘤侵犯或破壞了腎臟組織,導致出血。
Anemia and Erythropoietin (EPO): EPO is a hormone produced by the kidneys that stimulates the bone marrow to produce red blood cells. While it is true that impaired kidney function can lead to EPO deficiency, this is not typically the primary cause of anemia in renal cell carcinoma. More commonly, anemia in kidney cancer is caused by tumor invasion and destruction of kidney tissue, resulting in bleeding.
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