有關肥厚型心肌病變之病因,為主動脈狹窄。主動脈狹窄是指主動脈瓣口狹窄,導致心臟向主動脈泵血受阻。長期下來,左心室會因為要克服阻力而過度增厚,這是一種代償性改變,目的是為了維持血壓和心輸出量。
Regarding the etiology of hypertrophic cardiomyopathy, the statement "the cause is aortic stenosis" is incorrect. Aortic stenosis refers to the narrowing of the aortic valve, which obstructs the heart's ability to pump blood into the aorta. Over time, the left ventricle may thicken to compensate for this increased workload, aiming to maintain blood pressure and cardiac output.
而不是心肌炎、澱粉樣病變或酒精中毒,為什麼?
However, the true cause of hypertrophic cardiomyopathy lies elsewhere, not in conditions like myocarditis, amyloidosis, or alcoholic cardiomyopathy.
心肌炎:雖然心肌炎也會導致心肌變厚,但通常是急性或亞急性炎症反應,而肥厚型心肌病變是一種慢性進行性疾病。
Myocarditis: While myocarditis can also lead to myocardial thickening, it is typically an acute or subacute inflammatory response, whereas hypertrophic cardiomyopathy is a chronic progressive disease.
澱粉樣病變:澱粉樣病變是因異常蛋白質沉積在心臟而導致的心肌病變,與肥厚型心肌病變的病理機制不同。
Amyloidosis: Amyloidosis is a disease caused by the deposition of abnormal proteins in the heart, leading to a different type of cardiomyopathy compared to hypertrophic cardiomyopathy.
酒精中毒:長期大量飲酒可導致酒精性心肌病,但其病理變化與肥厚型心肌病變也不相同。
Alcoholic cardiomyopathy: Chronic excessive alcohol consumption can result in alcoholic cardiomyopathy, but its pathological changes differ from those of hypertrophic cardiomyopathy.
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